Late occurrence of clozapine-associated polyserositis
نویسندگان
چکیده
منابع مشابه
Clozapine-induced pericarditis, pericardial tamponade, polyserositis, and rash.
Sir: Clozapine is an antipsychotic medication introduced to the United States in 1989. It is a tricyclic dibenzodiazepine derivative chemically related to the traditional antipsychotic medication loxapine. 1 Side effects pose a significant problem during clozapine therapy. Adverse reactions occur most frequently during the initiation of clozapine treatment and during the acute treatment and dos...
متن کاملA Case of Polyserositis
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A 31-year-old white man was referred for investigation of a persistent sinus tachycardia. His only significant past medical history was of chronic schizophrenia for which he had been taking clozapine for six years. An electrocardiogram demonstrated sinus tachycardia, voltage criteria for left ventricular hypertrophy, and a prolonged QTc. Echocardiographic findings were consistent with a dilated...
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To the Editors: Clozapine is a tricyclic dibenzodiazepine derivative, atypical antipsychotic which exhibits relatively potent antiserotonergic (5-HT2, 5-HT3), antialpha1 adrenergic, antihistaminic (H1), antimuscarinic activity, and induces preferential blockade of dopamine D1 and D4 receptors in vivo. 2–4 Various adverse gastrointestinal effects have been associated with its use including const...
متن کاملInfection-associated clozapine toxicity.
Three case vignettes are presented documenting the rise in serum clozapine that occurred at a time of acute infection in these patients. The literature on this phenomenon is scant. The physiological processes that occur in the acute phase of the inflammatory response are summarized and provide an explanation of how clozapine levels may rise in response to infection. The risk of clozapine toxici...
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ژورنال
عنوان ژورنال: The International Journal of Neuropsychopharmacology
سال: 2006
ISSN: 1461-1457,1469-5111
DOI: 10.1017/s1461145706006961